20 Greatest Spider-Man Villains Ever

The wall crawler's most sinister foes.

Spider Mans Rogues Gallery
Marvel

With great power comes great responsibility and sometimes that responsibility can take the form of a boatload of villains trying to kill you.

Spider-Man is often considered to have one of the best rogue's galleries in comics. Through decades worth of adventures and over the course of numerous different series, he has built up a veritable smorgasbord of evil villains, filled with characters capable of wreaking havoc all on their own or together as part of the Sinister Six.

We've already seen the cinematic debuts of some of his worst enemies and, with Spider-Man: Homecoming gearing up the debuts of even more foes, now is a great time to take a look at some of Spider-Man's greatest enemies.

Get ready for a whole host of aliens, monsters and crimelords and a zoo's worth of animal-themed supervillains as we count down the twenty best enemies that Spider-Man has ever faced. They've all earned a place on this list, through devious schemes, raw power, pure unadulterated evil of just that special indefinable x-factor than can give a character staying power.

Just to spoil it now since we all already know it, Kangaroo is obviously number 1.

20. Mister Negative

Spider Mans Rogues Gallery
Marvel Comics

One of the newer villains on this list, Mister Negative was introduced as part of Spider-Man's sort of reboot Brand New Day and served as one of his main villains for that period.

A new take on the Jekyll and Hyde story, Martin Li is a philanthropist whose touch can cure others. However, when he transforms into his photo-negative alter ego, his power corrupts the souls of others and turns them into his puppets. Mister Negative has used this power to become a ruthless Chinatown ganglord and was even able to temporarily turn Spider-Man into one of his henchmen.

He is also served by his team of elite ninja bodyguards the Inner Demons.

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I was just a mild-mannered NCTJ accredited journalist until one day I found out the truth... that I could share my nerdy ramblings with people on the internet! It's just like mumbling to myself on the train, but without all the strange looks.