Throughout the entirety of the Marvel Cinematic Universe, we have seen Thanos trying to get his hands on the Infinity Stones. The Mad Titan has sent Loki after The Tesseract and Ronan after The Orb, neither with any success. However, it is hard to imagine Infinity War coming to a close without Thanos assembling all six stones within the gauntlet.
With The Black Order on his side, and any number of potential allies to call upon, will we see Thanos use more puppets, or will he live up to his promise made in the Age of Ultron post-credit scene and do it himself?
No matter how the stones come into his possession, as with any comic book adaptation, there will be comparisons to the source material. In 1990, Marvel released The Thanos Quest, a two issue mini-series following The Mad Titan on his journey to collect all six gems.
While at this point we can't guarantee how Thanos will achieve his goal, we can certainly predict and theorise, which for Marvel fans is almost as fun as actually seeing the movie itself. All we can say for certain right now, is that there will be very few similarities between the movie and the pages of the comics.