The Twist: With Uncle Ben already out of the picture this time, it'll instead be Aunt May (Marisa Tomei) who is offed by one of Spider-Man's (Tom Holland) foes, most likely Adrian Toomes aka Vulture (Michael Keaton).
Why It Could Ruin The Movie: Hasn't Peter Parker suffered enough? And do we really need to see another iteration of a grief-stricken Peter?
Plus, killing off May would just feel like a smug attempt to be subversive and keep fans guessing, rather than doing it because it actually services the story and characters in any way.
How Likely Is It?: Not that likely. Marvel Studios is (hopefully) smarter than this, especially with the film having numerous villains, new supporting characters and Tony Stark himself to juggle. Still, never say never. 4/10