Think about it, freedom from the daily grind, no bills to worry about, no boss to have a go at you and to top it off, you will enter the history books as a pioneer. Your name will sit next to Christopher Columbus and Neil Armstrong as someone who pushed humanity to the next level. Sounds enticing, but as with everything, there is a flip side to all the positives. With an expected launch date of 2021 and costing somewhere in the region of £4 billion, The Mars One Project setup an application process where people could apply to take a one way trip to Mars and be the first humans to try and colonize the red planet. From the 165,000 people who applied, only 4 will be chose to make the trip. But applying and being chosen is the easy part, what lays before them once they have made the grade is something that will test their body and mind to the limit. Being one of the first group of people on Mars is a romantic notion, but it could very easily turn into a nightmare. You might have fame and escape from the pressure of life on Earth but once the problems kick in, there is no option to quit and turn the craft around. So spare a thought for the applicants, they might be reveling in the buzz now but they might have just made the biggest mistake of their lives as we show you the 10 ways the trip to Mars will screw up their health.