10 Most Dangerous Spider-Man Villains

10. Mysterio

On the surface, it doesn't seem like Mysterio would be a very dangerous foe. After all, he has no superpowers of his own, and he's little more than a master of stagecraft and special effects. Despite this, he's become one of the most dangerous enemies Spider-Man has faced over the years.

This was clear to anyone who saw Spider-Man: Far From Home, but even Jake Gyllenhaal's outstanding performance of the character's drive was just a taste of what Mysterio is capable of when going up against Spider-Man. His obsession with theatrics and ability to create a scene has caused a lot of problems for ole' Web-Head over the years.

He once had him convinced that he was shrunken down to only a few inches in height, and he's played off increasingly dangerous and deadly theatrics to achieve his goals. Interestingly, he's still a threat to Spider-Man despite his Spider-Sense, and it often takes a lot of work for Spidey to defeat him.

Still, he's not perfect, and he is just a man. He's dangerous enough to find a place on this list, but he's kicking it off at number ten due to the fact that there are ways to counter his illusions. He's gone up against Daredevil a time or two, and the Man Without Fear doesn't fall for his tricks, so a team-up can often render him innocuous.