10 Times Superheroes Fought The WRONG Villain
10. Daredevil And Mysterio - Guardian Devil
If you want good old fashioned comic book weirdness mixed with eighties gen-x cynicism, look no further than the library of work by one Kevin Smith. And nowhere is this mix more starkly apparent, for good and for ill, than in his brief tenure on Daredevil. Specifically, when Daredevil took on Mysterio in the Guardian Devil storyline.
Frankly, any storyline involving Mysterio has no right to be anything other than wacky comic book goodness. In this story, Mysterio tricks a teenage girl, and by extension Daredevil, into thinking she's pregnant with the antichrist, due to being diagnosed with an inoperable brain tumor and wanting to go out by driving Daredevil mad.
After some insane and tragic shenanigans, including the murder of longtime love interest Karen Page, Daredevil finally runs Mysterio down and does the worst thing you can do to someone as obsessed with showmanship and appearances as he is: he riffs his scheme to pieces and berates him as unoriginal, pointing out how previous villains have done the exact same thing he did, and always unsuccessfully.
Realizing that he failed to break the Man Without Fear, and not wanting to go out via some brain tumor slowly killing him, Mysterio kills himself straight after.