Sure, everyone was shocked and saddened to watch Gwen Stacy bite the dust in The Amazing Spider-Man 2, but if Sony wants to find a moment that will really go for the emotional jugular of the moviegoer, the studio can adapt Aunt Mays death (which was criminally retconned a few years later) from Amazing Spider-Man #400. The Gift is considered by many readers to be one of the greatest Spidey stories of all time as it is written and illustrated with the utmost tenderness and earnestness by J.M. DeMatteis and Mark Bagley. In this comic, May emerges from a coma long enough to spend one more day with her nephew, Peter. Over the course of this day, she reveals that shes known hes been Spider-Man for years (which was also retconned away when May was resurrected), before eventually asking to return to her home in Queens so she can die peacefully. As shes dying, Peter recites the famous line from J.M. Barries Peter Pan about finding the magical place Neverland by looking second to the right and straight on till morning. Someone must be cutting onions as Im writing this because my keyboard is all wet. The emotional gut punch of watching the matriarch in Spider-Mans family peacefully die while her nephew/surrogate son recites lines from a childhood story would guarantee a theater full of sobbing children and adults.