10 Movie Characters Killed Early In The Sequel

10. Irene Adler - Sherlock Holmes: A Game Of Shadows

There was always a special relationship between Sherlock Holmes and Irene Adler, and one that stretches back before the beginning of the first movie. Though obviously very fond of each other, Adler can never commit to being on the same side as Holmes.

In the sequel, A Game of Shadows, Adler is working for Moriary against Sherlock, being used as a middle man between the two. After a "date" between Adler and Holmes, Moriarty decides that she is too close to his adversary, and poisons the American.

This demonstrates the ruthlessness of Professor Moriarty, showing such indifference in killing someone that means so much to Sherlock Holmes, setting the tone for Jared Harris' incredible portrayal of the villain.

For the rest of the movie, Sherlock has to face Moriarty with a psychological disadvantage, knowing how little regard his nemesis has for anyone who gets in his way.