10 Scariest Mad Scientists In Horror Movies

10. Victor/Henry Frankenstein - Frankenstein

There is no way you can discuss mad scientists without thinking about Dr. Frankenstein. Even though the iconic chemist debuted in Mary Shelley's Frankenstein novel in 1818, it was Colin Clive's performance in the 1931 film that popularised the deranged doctor trope. Much like the creature that Frankenstein revives, Clive is responsible for breathing life into a crucial archetype in the horror genre.

Interestingly, Frankenstein is depicted very differently in the source material. When the Monster comes to life, Victor is ashamed of his creation and shuns it. But in the film, Frankenstein (who's forename was changed to 'Henry'), goes mad with power, pontificating to the heavens and comparing himself to god.

By today's standards, overdramatic performances from this era can come across as hammy and theatrical. However, Clive is so compelling and convincing in his deranged ramblings, you completely buy that he believes what he's saying.

There have been countless mad scientists over the years but they all share a common trait with Clive's rendition of Frankenstein - their uncompromisable compulsion to perform the impossible drove them completely bonkers.