The Actor: Comedienne Amy Schumer is better known for her stand-up and TV work such as Inside Amy Schumer, though writing and starring in Judd Apatow's new movie is sure to do wonders for her career. The Role: Schumer plays Amy, the titular trainwreck who has rejected the notion of monogamy ever since childhood, though finds herself questioning her boozy, promiscuous ways when she meets a charming sports doctor, Aaron (Bill Hader). Why They Might Win: Because while Apatow's films aren't exactly synonymous with awards fare, the Academy will take huge note of not just Schumer's transition to big-screen work, but also that she wrote the film herself. Plus, if they can give Melissa McCarthy an Oscar nomination for taking a crap in a sink in Bridesmaids, why can't they reward a female role that looks like it has a little more dramatic meat on its bones?