15 Doctors Crazier Than Hannibal Lecter

15. Dr Sebastian Caine - Hollow Man

Cocky, self-assured and labouring under an ego the size of Texas, Sebastian Caine considers himself a god among insects. So driven is he to make history that he has no time for relationships, much to the chagrin of his former girlfriend.

After discovering the secret of invisibility, he uses himself as a test subject, and you know what that means. What starts out as fun and games, though, quickly turns sinister when the lack of sleep (his eyelids are invisible, after all) takes its toll on his mental health.

After attacking his neighbor, Caine returns to the lab and, hunted by his colleagues, leads them on a cat and mouse game through the facility, during which he picks them off one by one.