I dont think this subject got enough attention in Star Trek: Into Darkness. Khans origin was barely touched on and the idea of his genetic alterations barely got more than a nod of notice. In fact, it was more surprising that he was from the 20th century. His backstory was more of an explanation for his presence rather than an issue worth notice. When Julian Bashir from Star Trek: DS9 was discovered to be illegally genetically altered (Doctor Bashir, I Presume) it caused plot complications and character ramifications for episodes afterwards. In Into Darkness, Khan was simply a threat to overcome, with no apparent regard for his altered status. When you consider the TOS episode Space Seed spawned an entire motion picture, the audience really needed more introduction and appreciation of Khans status in Into Darkness than just simply a villain. Genetic alteration is a serious issue within the Federation as we can see from the behaviour of Bashirs parents. Why didnt it get more regard in Star Trek II? Maybe this is something that can be addressed in Star Trek III.