Almost all spin-offs occur in a new setting. The new setting is part of what makes the spin-off fresh and new. It clues the viewer in right from their first glance that this is a different show. Supernatural has always had a shifting setting. The show involves two brothers on an endless road trip through the U.S. But as the show evolved, the detail of the small towns they passed through fell to the wayside. Each setting used to be developed so well that there was a sense that life existed before the Winchesters rolled into town and would go on after. Viewers met several citizens of the town who had fully developed lives and conflicts. The Winchesters were just guests passing through and the events would have unfolded whether or not they existed. Just with slightly less happy endings. As the show evolved, the conflict shifted to revolve around the central cast. Ninety percent of the time if it wasn't for Sam, Dean, and Cas, the ordinary citizens wouldn't be in danger at all. Viewers are rarely introduced to more than one or two bumbling, super-stereotyped people of the town, and the rich details of the towns they visit faded into obscurity in favor of more time and attention focusing on the main characters.