We had back to "Not All Dogs Go To Heaven" for this one. Patrick Stewart has appeared in several Seth MacFarlane properties and is a big part of American Dad as Stan's boss, but having the entire cast of Star Trek: The Next Generation was a stroke of brilliance and an absolute coup for the show. In all goes down when Stewie, a huge fan of the show, transports the entire cast to him so he can meet them and ask questions as only an excitable young fan can. However, he soon finds the cast annoys the hell out of him. The cameo works thanks to each member being committed to poking fun at themselves (several had been on the show previously), and because of solid attention to detail, such as Denise Crosby being killed off early, just as her TNG character Tasha Yar was killed off on the show early on.