10 Actors Who Appeared In Star Trek AND The MCU

3. Zoe Saldaña

Zoe Saldaña won the Oscar for Best Supporting Actress at the 2025 Academy Awards, though sadly it wasn't for her MCU or Star Trek roles. She first appeared in Star Trek, portraying a thoroughly modernised version of Nyota Uhura. She brought a confidence and freedom to the role that Nichelle Nichols, who, of course, originated the role, while oozing the former, was never afforded the latter. 

In Star Trek and Saldaña's portrayals, Uhura became the main character she was always destined to become. Her interactions with Chris Pine's Kirk and particularly Zachary Quinto's Spock helped boost the energy and efficacy of the film overall, as did her appearances in the two sequels.

In the MCU, she plays Gamora, daughter of Thanos, and an occasionally deceased member of the Guardians of the Galaxy. Having appeared in all three Guardians films, as well as Avengers: Infinity War and Avengers: Endgame, she has now appeared in some of the highest-grossing films ever made. Though she has not, at the time of writing, been confirmed to appear in Doomsday, it is unlikely that the MCU would pass over this star. That new statuette is probably going to be quite the bargaining tool going forward.