The prequel opened up the opportunity to ask a lot of interesting questions. We knew the fate of the characters, but how would they interact with that fate? Would the see it coming? Would they fight it to the last? If Anakin knew the end of his path, what would he do? The movies completely ignored these questions, but Clone Wars occasionally played around with them. There was an episode where Anakin got a vision of the future, was faced with Vader, and reacted with terror and revulsion. He was willing to do anything if he could stop that fate. Thats the biggest one, but there were moments scattered here and there that played with the fact that we knew the future. The show pulls no punches about the fact that Palpatine is Sideous, unlike the prequels. At one point, Obi-Wan fakes his own death, and Anakins grief-fueled reaction to that is central to the plot. And, of course, its really hard to get attached to the Jedi younglings when you know theyre going to be sliced to pieces in a few years.