5. I am Hannibal Lecter
The part of Lecter was coveted by most actors with a long list of Oscar winners including Robert Duvall, Jack Nicholson, and Robert De Niro all being considered. Plus a tidy British contingent including Patrick Stewart, John Hurt and the original Hannibal from Manhunter Brian Cox all auditioned. Jeremy Irons was chosen as the stand out candidate, which actually makes great sense and I can quite easily imagine how his Hannibal might have been. Irons turned it down, but did not live to regret it as the part he chose over it was Claus Von Bulow from Reversal of Fortune, which he, like Hopkins would go on to do, won Best Actor.