6. The Biblical Apocalypse
You don't get much more significant than the Biblically-ordained end of days. Biblical apocalypse films are usually based around the birth of the Anti-Christ, which tends to involve a whole lot of omens. As a result, the Biblical apocalypse genre tends to be overly portentous and cheesy as hell. There's always a morally righteous individual, who, willingly or otherwise, gets caught up in Lucifer's return; ironically, the incarnation of the Devil, twisted, charming and amoral, is almost always the best part of the film (End of Days, Constantine, The Prophecy). This would be ironic if such films had much of a sense of irony, but, unfortunately, every one I can think of (from Legion to The 9th Gate) is played depressingly straight. That's not to say they're not fun, but, unlike for instance the natural disaster apocalypse, they have a habit of taking themselves too seriously. It's for this reason, if no other, that This Is The End, the Seth Rogen-James Franco-too many other celebrities to count comedy, is a breath of fresh (if somewhat sulfurous) air. The Biblical apocalypse is defined by clearly delineated good and evil - it has The Devil as an antagonist so things tend to be pretty unambiguous on that front -, so it's nice to have protagonists for once who's not so much "tormented but fundamentally good" as, well, just assholes. There's also a giant swinging demon cock. Dignity be damned, it's funny.