19 Awesome Movie Cameos Nobody Saw Coming
14. George Clooney - South Park: Bigger, Longer & Uncut
After Kenny horribly burns himself attempting to light a fart on fire, he's rushed to hospital where a doctor known only as "Dr. Doctor" attempts to save his life.
However, the doc and his team accidentally replaces Kenny's heart with a baked potato that was sat in the microwave, giving him just three seconds to live before the potato explodes out of his chest.
Clooney just has a few scattered lines as the doctor, but at the time it was simply so bizarre to hear an A-list actor lending their voice to...South Park.
This wasn't actually the first time he was involved with the show, though: he "voiced" the gay dog Sparky in the very first season, being an early champion of Matt Stone and Trey Parker's creation and offering his support.
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