50 Funniest Comedy Movie Moments Since 2000

The Movie: Four friends take off on a cross country road trip to retrieve an illicit tape mistakenly mailed to a girlfriend. Along the way things, of course, get out of hand. 

The Scene: Seann WIlliam Scott provides the best supporting evidence that the male G-spot exists since Dr. Ruth, which will make you look at your yearly doctor's visits in a whole new light. 

Of course, your doctor will never be as sexy as this ambitious nurse, who goes to kinky ends (literally) to make sure her patient provides the material she needs. As expected, Scott's ejaculation expression is appropriately douchey.

Memorable Quote: "I'm gonna perform a procedure on you called milking the prostate. It's an anally-induced ejaculation."