5. The Villain
The Original Version... took one of Spider-Man's most iconic and feared villains, the Green Golbin, and made him look like a rejected Power Ranger. The man portraying him - Willem Dafoe - is an excellent actor, but was masked through most of the film. Although to be fair, he looks more scary without the mask on.
But the Reboot... took another of Spidey's most famous foes - The Lizard, whom we had never seen on the big screen - and made him arguably more powerful and fearsome than in the comics. They also gave plenty of screen time to the actor playing the role, while not getting so bogged down in his life that they neglected his alter ego (you know, the Lizard).
The Winner... is definitely the 2012 version.