4. Seth MacFarlane
Technically MacFarlane shouldn't be on this list as he was never specifically a Roaster, but was invited to be the Roast Master General on 3 separate occasions, which means that I'll give him a free pass this time. Seth is best known for being the creative talent behind Family Guy, as well as large roles in the production of American Dad and Family Guy's spin-off the Cleveland Show. MacFarlane was the Roast Master of the David Hasselhoff, Donald Trump and the Charlie Sheen Roasts in succession. MacFarlane played the role of the Roastmaster to a tee, insulting all comers with his tenacious zingy wit that was apparent in all of his work. MacFarlane uses a mixture of both clean and dirty jokes to insult the various daises (according to Wiktionary this is the plural of dais), while for most of MacFarlane's jokes on lesser known comedians are regularly about how no one knows who they are,
BestJoke Introducing Former Heavyweight Champion Mike Tyson "Tyson has beaten every opponent he has gone up against, apart from the letter S."