The first recorded instance of tragedy directly affecting a film production was Buster Keaton's silent comedy Steamboat Bill Jr, the ending of which had to be hastily rewritten after the Great Mississippi River Flood of 1927 hit the area, causing widespread devastation and displacing countless families in the Mississippi Delta.
While Keaton at least had the benefit of the tragedy - the most destructive of its kind in US history - taking place before shooting began, countless filmmakers since have not been so lucky. The 9/11 terrorist attacks affected a great many number of films shot in New York City, one of which was Ben Stiller's offbeat comedy Zoolander.
The film, which was released a little over two weeks after the attacks, featured shots of Manhattan's famous skyline, leaving Stiller with an impossible choice to make - leave the Twin Towers in and risk upsetting his audience or digitally remove them. He went with the latter, deeming it the lesser of two evils, though it didn't stop him from coming under fire from a number of critics for his decision.
As films fans, we like to believe that nothing is more important to us than a good movie, though when a real tragedy takes place we are instantly reminded that this is not the case. Life always comes before art, and cinema, as you're about to see for yourself, has never been an exception.
With causes ranging from natural disasters and terrorist attacks to child molestation and murder, here are 10 films that needed to be altered because of real life tragedy...