4. Wolverine and The Hulk
Wolverine got his start in The Incredible Hulk, where he starts by attacking The Hulk. The two have a lot of battles in Marvel comics, and other times they work together. In the Ultimate universe, Wolverine is even tasked by Nick Fury with bringing in an out-of-control Hulk at one point. This kind of tumultuous relationship would work great on the big screen, possibly in the next Hulk movie. Obviously, the greatest appeal is one of Marvels smallest super heroes against one of the biggest. Add in that Wolverine cant pierce Hulks skin, and Hulk cant kill Wolverine with punches alone, and theyre a perfect match for an epic battle.