6. Dr. Richard Kimble vs. Dr. Charles Nichols - The Fugitive
This is a movie so full of mismatches it's hard to actually keep track of them. Firstly, you've got Dr. Richard Kimble (Harrison Ford) escaping from his prison transport and becoming the titular fugitive, causing him to be pursued doggedly by every policeman in the state, and yet he still
manages to stay ahead despite a few close encounters. Then there's Kimble against Dr. Charles Nichols (Jeroen Krabbe), the dude who we discover was really behind his wife's murder all along. When a surgeon is facing off against a research doctor, it's hard to know who is more mismatched with who, until the later stages of the film when Nichols suddenly turns into an unexpected badass and manages to easily disarm a U.S. Marshall (played by Joe Pantoliano, no less) while proceeding to finish Kimble off. Taking Kimble's hard-as-nails colleague on his own terms, it has to be deduced that Kimble, whose trajectory throughout the film is easier defined by luck than anything, is the weaker link, no matter how many fast-moving objects they want to Photoshop him next to in order to make him seem more tough and cool.