7. Oprah Winfrey - Lee Daniels' The Butler
The Film: Lee Daniels' controversial film revolves around a black butler named Cecil Gaines (Forest Whitaker), who during his employment at the White House in the 20th century, comes to personally witness countless notable events in American history. Oprah will play his wife, Gloria.
Why She Could Win: Buzz on this one is riding the inside track so far in the Best Supporting Actress race, suggesting that director Daniels could have another Mo'Nique situation on his hands. Given Oprah's popularity all over the world, and how much Oscar voters love seeing unconventional actors giving prestige performances, consider this one a major threat.
Other Talent: Oscar winners Robin Williams, Forest Whitaker, Jane Fonda, Cuba Gooding Jr. & Vanessa Redgrave, Oscar nominees Lee Daniels (director) & Terrence Howard.