5. Mole Man
Although he's not exactly the most formidable villain, this would be a respectful nod to the first ever Fantastic Four comic way back in 1961 and he could be an ideal foil for Doctor Doom. Mole Man is the original Fantastic Four villain and has a genius level intellect to somewhat rival the group's science expert Reed Richards, whilst also possessing fairly formidable combat skills with a staff. His genius gives him a knowledge of technology that is centuries beyond conventional scientific development. In the comics, he was able to master alien principles of technology that were totally foreign to his culture and environment. Thanks to his poor eyesight, his other senses have naturally compensated to the degree that they are, like those of Daredevil, heightened to almost superhuman levels. His staves were designed by the Mad Thinker (someone who we'll learn more about shortly and someone with whom a team-up in a Fantastic Four movie might be a good idea) and they contain devices and gadgetry such as ranged weaponry to make him even more dangerous in combat. He shouldn't be allowed to carry the villainous mantle on his own, but alongside another villain on his level or as a completely separate villain to Doctor Doom, he could be a nice addition to a live action Fantastic Four movie.