50 Funniest Comedy Movie Moments Since 2000

The Movie: Seth Rogen stars as Ben Stone, a young, work-shy layabout who lives with his equally worthless friends and spends his days smoking weed, drinking beer and watching pornography. 

He lives off compensation he received from an injury years earlier, and him and his pals are attempting to start up a celebrity porn website. On a random night out, Ben has a one-night stand with the successful, attractive Alison Scott (Katherine Heigl), who later realizes she is pregnant.

The Scene: Under the heavy influence of psychedelic mushrooms, Ben and his new-found married friend Pete (Paul Rudd) discuss both of their current romantic relationships as well as become adequately freaked out by the number of chairs in their hotel room.

Memorable Quote: "The tall one's gawking at me, the short one is being very droll."