9. Skye's Real Identity
Mutant Enemy ProductionsThis is a real long shot, but there is a slight chance it could happen. Skye's true origins are as yet unknown and she has been described as an 0-8-4 (the name given to objects of unknown origin by S.H.I.E.L.D.) and it has been hinted that her actual origins may give her superpowers - albeit superpowers that are yet to manifest. The first season of Agents of S.H.I.E.L.D. came to a close with Skye's father having been ever so slightly "revealed" (a dripping bloody hand was seen only) and we still don't know exactly who or what Skye really is.
Fan theories regarding her true identity include She-Hulk, Ms. Marvel, Phyla-Vell, Spider-Woman and Mantis and, if any of those bigger names turn out to be who Skye really is, there's every chance she could become a big player in the Marvel Cinematic Universe. If that turns out to be the case, and Skye ends up starring in the bigger budget and more widely watched movies, the very gorgeous Chloe Bennet could quite easily become the new face of the franchise.