What If Andrew Garfield's Amazing Spider-Man Had Joined The Avengers?

1. Sinister Six

This version of the Sinister Six would take some inspiration from the Insomniac PS4 version combined with the existing Amazing Spider-Man lore. The movie being Doc Ock's origin movie as well as being a clash with the Sinister Six and Spider-Man.

As it turns out, Doctor Octavius had been a scientist at Oscorp on the night of the Lizard attack, but Gwen's evacuation and Peter's use of the cloud burster had ruined his research and he suffered adverse effects of the cure. As such, this has led to him growing a grudge against Peter and led to him adopting the tentacle harness in order to support his now significantly crippled body.

It would involve this incarnation of the Sinister Six dealing Spider-Man his biggest blow by nearly completely killing him and leaving him emotionally broken as well. Whilst recuperating, Peter is left clueless how to stop the Sinister Six but is surprised when Matt shows up with The Defenders and Vision in order to provide him some backup. This movie also estranges Peter and Harry for good, with no hope of reconciliation when Harry wants to kill Mary Jane 'just like with Gwen the last time'

Eventually, Peter is able to beat back the Sinister Six with help from his friends and proceeds to lock all of them up in the Raft. Peter and Mary Jane finally decide to become a couple and share a kiss together. With this, Oscorp has gone bust and the building has been sold to a mysterious benefactor who decided to rename it as the Baxter Building.

Of course, all of this is only a mere speculation. It would have been interesting should The Amazing Spider-Man be maintained but Tom Holland appears to be doing a great job portraying the web slinger in the MCU. His appearance in Civil War, the Infinity War Sage, Spiderman: Homecoming and Spiderman Far From Home has been nothing but spectacular.