17 Mind-Blowing Facts You Didn't Know About Mass Effect
10. The Game Will Respond If You Probe Uranus
If you already have a particular way of thinking you might have already found this one.
In Mass Effect 2 as part of the game is mining for various types of materials in an open galaxy, if you take your ship over to Uranus (literally any sentence with that planet is always funny) and launch a probe, EDI will remark "Really Commander?" before saying "...probing Uranus" like some friend who's sick of "That's what she said" jokes.