20 Toughest Video Game Characters Of All Time

10. Isaac Clarke

First Appearance: Dead Space (2008) Isaac Clarke was a normal ship engineer (if you consider working on space ships normal) who had fallen in love with a co-worker. When the ship his love - Nicole - was on sends out a distress signal, Clarke volunteers to be part of the crew sent to investigate hoping he ascertain the fate which has befallen his woman. On the ship, the crew are attacked by monsters leaving only Isaac and two others alive, which after discovering these monsters are infected humans, Isaac becomes more desperate to find Nicole. After seeing her but not being able to meet, Isaac is betrayed and left for dead by one of his crew members. It is then revealed that Nicole is actually a hallucination and the real Nicole killed herself days ago. Not only was he heartbroken but he was then captured by government forces. So, a heartbroken man has to fight killer aliens while seeing visions of his dead girlfriend in order to prevent them taking over the universe... you can't deny this guy is tough. Armed with an awesome array of both engineering tools and €“ more boring €“ conventional weaponry, Isaac Clarke is arguably one of the loneliest men in all of video gaming and must fend off corridor-after-corridor of some of the scariest enemies we have seen come out of an console in recent years.
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Hailing from South East London, Sam Heard is an aspiring writer and recent graduate from the University of Warwick. Sam's favourite things include energy drinks, late nights spent watching the UFC with his girlfriend and annihilating his friends at FIFA.