4. South Park
Main Character Missing: Stan, Kyle, Cartman and Kenny.
Which Episode?: Numerous.
Is It Still Good?: Episode Dependent. South Park is often wrongly written off as a dumb show. Those people would be partially correct, but only partially. Through its crudeness, Matt Stone and Trey Parker are two incredibly talented and rather intelligent and satirical individuals, which is why the show has lasted for so long. That's not to say they've never had their off-episode. "Eat, Pray, Queef" anyone? There are numerous other episodes, such as Season 2's "Terrence and Phillip in Not Without My Anus" and recent ventures such as "Goth Kids 3: Dawn Of The Posers". Judging these episodes on quality would take far too long, so let me just say that this is usually a clever show and any episodes without the four boys should be treated the same.