The Seventh Doctor lands the TARDIS in New York, but the ship appears in the midst of a gang shootout, and The Doctor is caught in the crossfire, causing him to regenerate. Due to human attempts to help save The Doctor from his bullet wound, his regeneration is tampered with, leaving the newly-regenerated Eighth Doctor with amnesia. Whilst this happens, The Master has taken over the body of an American paramedic, and begins work attempting to steal the remainder of The Doctor's regenerations, as he has already expended his own thirteen lives...