5. Itchy
Voiced by Dan Castellaneta, Itchy is the mouse who provides Bart and Lisa with endless hours of entertainment by slaughtering Scratchy in the "Itchy and Scratchy Show". In the show, Itchy and Scratchy become embroiled in elaborate rivalries, in which Itchy invariably prevails, nearly always by brutally murdering the cat. But what if the show's writers put the boot on the other foot and gave Scratchy a rare victory in a battle to the death? It might seem unlikely, given it would mean the end for the Itchy and Scratchy Show, but isn't it time the annoying rodent finally got his comeuppance? Some bookies have Itchy
pegged at 8/1 to be killed off in season 25.