Supernatural: 20 Greatest Music Moments

8. "Rock Of Ages" By Def Leppard (5.22, "Swan Song")

In the episode that was originally intended to be the finale of the entire show, Sam has assented to becoming Lucifer's vessel as part of a Winchester plan that doesn't work at all. Meanwhile, their half-brother Adam takes Dean's place with Team Heaven and becomes the vessel for archangel Michael. Lucifer/Sam and Michael/Adam meet alone on the final plane of battle. Castiel warns Dean that there is nothing that he can do to save his brothers. Dean says that he will not allow Sam to die alone. So, in classic Dean style, he drives up to the battlefield in the Impala, blasting "Rock of Ages" out of the speakers.

7. "Smoke On The Water" By Deep Purple (6.2, "Two And A Half Men")

After the events of "Swan Song," Dean determinedly embraces suburbia, even going so far as to cover the Impala with a blanket and hide her away in the garage. Nevertheless, when Sam returns, Dean falls all too easily back into the hunting lifestyle when faced with the case of a shapeshifter baby (which he puts to sleep by humming the Deep Purple song). Still, Dean resolves to honor his commitment to girlfriend Lisa. Lisa, however, tells Dean that he is free to return to his life as a hunter with his brother, and that she will be there whenever he can come back. So, with "Smoke on the Water" beginning to play in earnest, Dean goes into the garage and whips the dust cover off of his one true love. He's back!