10 Worst Things That Ever Happened To Deadpool
5. Killed The Entire Marvel Universe, Twice - Deadpool Kills The Marvel Universe
Following the failed attempt of a D list supervillain to brainwash Deadpool, the fallen hero developed a new, more murderous voice inside his head, which pushed him to kill every single hero, villain and superpowered deity in the Marvel universe.
From Spider-Man and Doctor Doom to Howard the Duck and even Galactus, Deadpool carved a bloody path showing how complicit the heroes and villains of the world had grown in their belief that they can never be killed.
This rampage was eventually stopped, but it did not prevent another Deadpool from being successfully brainwashed in the 2017 series "Deadpool Kills the Marvel Universe Again," which saw Wade be turned into a puppet for the supervillains of the world led by the Red Skull, slaughtering every single superhero until he was reset with a trigger word that turned him against the villains as they celebrated their victory.
By the end of both stories, Wade was left covered in blood wishing for the same thing he's always wanted - punishment for his sins.