2. Owen Wilson, Anaconda
As an ever present figure on the silver screen, funnyman Owen Wilson is a household name. Yet, way back in 1997, this wasn't necessarily the case. In only his third credited acting role, Wilson played the part of a minor character in the adventure-horror, Anaconda; the ominously titled story of a National Geographic film crew who bite off more than they can chew when they venture out into the Amazonian rainforest. The team, who enter the Amazon in search of a lost Indian tribe, stumble into contact with Paraguayan snake hunter, Sarone (Jon Voight), who promises to lead them to the tribe. After a while, they discover that they have unknowingly been taken hostage by Sarone, who plans to utilise them in capturing a freak sized anaconda. With this knowledge, the crew decide that their best means of survival is to abandon Sarone and fend for themselves. Of course, Wilson's character Gary disapproves of this idea and, ultimately, pays the price by acting as snake fodder for the man-eating anaconda. Although relatively forgettable, the film is most memorable for its tongue-in-cheek humour and for the way in which it single handedly increased the level of sufferers of ophidiophobia; though, thinking about it, I might just be speaking for myself on that latter point.