10 Great Horror Movies Turning 20 In 2025

8. Antibodies

The Descent Ending
Kinowelt Filmverleih

If Jonathan Demme’s The Silence of the Lambs and David Fincher’s Se7en are considered psychological/crime thrillers with substantial horror cred, writer/director Christian Alvart’s Antibodies should be as well.

In fact, it functions like a hybrid of those two masterpieces, and it might be the scariest of them. The opening scene alone is incredibly gripping and ghastly, with pederast murder Gabriel Engel operating on his latest victim moments before being captured by police during a Fincher-esque grimy storm.

From there, Engel challenges naïve officer Michael Martens (and his colleagues) just like Hannibal Lecter exploits Clarice Starling, cleverly manipulating every officer who interrogates him. All the while, Martens is determined to prove that Engel murdered 12-year-old Lucy, too, and their cat-and-mouse battle of wits and morality is as absorbing as it is bluntly macabre.

The last act is particularly suspenseful and alarming due to its bleak assertions and potential outcomes, as Engel confesses that he saw Martens’ teenage son – Christian – kill Lucy. There’d already been hints about Christian’s homicidal tendencies, and unfortunately, Martin decides that he must kill his son to prevent him from becoming like Engel.

We won’t spoil how Antibodies wraps up, but suffice to say that it’s very satisfying.

 
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Contributor

Hey there! Outside of WhatCulture, I'm a former editor at PopMatters and a contributor to Kerrang!, Consequence, PROG, Metal Injection, Loudwire, and more. I've written books about Jethro Tull, Opeth, and Dream Theater and I run a creative arts journal called The Bookends Review. Oh, and I live in Philadelphia and teach academic/creative writing courses at a few colleges/universities.