6. Cobb (Leonardo DiCaprio in Inception)
Cobb is one of the only character that was created in this decade (and some would argue that 2010 was part of the 00s, not the 10s). This tells you a lot about the state of movies today where nothing is ever truly original, everything is just a remake, sequel, reboot or inspired-by movie. But Dominick "Dom" Cobb is different. Hes a con artist with a very specific M.O., motivation, and crew. Hes seen it all in the dreamscape, and is the only one ever able to have escaped Limbo (twice!). One could argue that his appearance is not that memorable, but think about his spinning top for a minute: isnt that a memorable attribute? It is one of DiCaprios defining role already, and the movie has entered the Hollywood Annals with its score, its SFX, its themes, its story, and most of all its character!
Runner-up: Ted, from Bill & Teds Excellent Adventure. I chose Ted over Bill because Ted is the first one to think about going back in time and warning them to Duck at the important moment.