6. Charlize Theron - Monster (2003)
To portray her role in the film Monster, actress Charlize Theron packed on 30 pounds and underwent some impressive make-up effects in order to accurately play real-life killer Aileen Wuornos. Theron, who was once voted the Most Desirable Woman Alive, managed to ugly-up one of the prettiest faces in Hollywood in the chilling and controversial role. And she pulled it off to great effect, sweeping the Oscars, Golden Globes and Screen Actors Guild Awards for Best Actress.