2. Venom
Who Is He? The result of a parasitic alien Symbiote bonding with Daily Bugle photographer Eddie Brock.
Why Would He Make A Good Villain? Venom is basically what Peter Parker would have been when attached to the Symbiote if he wasnt such a good person. Hes Spider-Mans evil counterpart which is what makes him such a credible villain. None of Spider-Mans powers can give him an advantage because Venom has pretty much the same powers only stronger. Because he would be fighting a merciless and stronger version of himself, Spider-Man would be stretched to his absolute limit physically. Which would be a good way to develop his character more while finally showing a different side to his being a superhero than him just swinging by and beating up the bad guy. If any villain can bring down Spider-Man, its Venom. And because Eddie Brock knew Peter Parker before he bonded with the Symbiote, it would help him attack Peter psychologically since them being colleagues means that Brock has a basic understanding of his personality and psyche. But if Venom was going to be used, hed have to be the primary if not the only villain with him battling Spider-Man at least twice and bringing widespread chaos and destruction to New York. Not the failtastic way he was shoehorned into Spider-Man 3 at the last minute and woefully underused as a result.