Avengers 4 Trailer Decoded: Every Character Analysed & Explored
3. Bruce Banner
After his performance issues in Infinity War, Bruce Banner is probably going to be continuing on the same arc of finding some balance between Bruce and the Hulk as well as wrestling with the guilt of not being able to stop Thanos by Hulking out in Wakanda. It may not have done any good, but when you're a walking weapon of mass destruction that's bound to play on your mind.
That may be why we see him so visibly tortured by the deaths of his team-mates in the Avengers facility sequence of the Endgame trailer. Though, that's inevitable too, since he's arguably the most emotionally volatile of all of the Avengers.
Bruce will probably be behind the plan to go back in time - or through the Quantum Realm to another point in time - along with Tony Stark, Scott Lang and probably Erik Selvig. The brain trust plus Scott (though his experience in the Quantum Realm is what counts here).