10 Video Game Fates Worse Than Death (Commenter's Edition)
9. Turned Into A Surgically Altered Slave - Half-Life 2
And you thought being turned into a Headcrab Zombie was bad.
Though not nearly as common as Headcrab Zombies, Stalkers appear in Half-Life 2 as the grotesque, humanoid guardians of the Citadel's core.
Once upon a time, every Stalker was a regular human being who was believed to be an "undesirable" by the Combine, causing them to be sent to the prison Nova Prospekt.
There, their extended limbs are removed and replaced with metal augments, while the majority of their organs - including the digestive tract, vocal cords, and genitalia - as well as most muscle and fat are removed, and their brains likely tampered with.
Basically, the experiments turn the victim into a compliant slave, a far cry from their former selves, ensuring they only exist in the most basic, technically correct sense of the word.