22. Del Lago (Resident Evil 4)
https://www.youtube.com/watch?v=VYH8qtNpg4o The ongoing battle between man and the creatures under the water is a tale as old as time, which makes Resident Evil 4's boss fight against the sea-dwelling beast known as Del Lago all the more fantastic. There's certainly a great debt owed to films like Jaws and The Abyss, an eerie tension that soon becomes all-out survival for Leon Kennedy. The thrill of hunting and being hunted, it's all played expertly with this epic battle on the water that never fails to entertain. It's a mix of fast-paced fun while Del Lago drags your boat across the water, just begging you to pelt it with your unlimited supply of harpoons and the straight up horror of not knowing where it is as it stalks your pitiful little boat. It's a boss fight that asks the most out of you, testing every limit of your endurance and will to win. It's a constant challenge, daring the player to come back to its murky waters again and again.