21. Bowser (Super Mario 64)
https://www.youtube.com/watch?v=xDhxfUBrMko Among the many times that you have steered Mario to victory against his arch-nemesis, the King Koopa himself Bowser, there was no battle against him that was more rewarding than the trio of battles in Super Mario 64. Taking place in the Dark World, the Fire Sea and the Sky, the three Bowser battles continue to up the ante with each one until the third fight becomes a delightful struggle to maintain your sense of focus. The evolution of these battles takes you on a challenging journey, and is one of the key elements that makes Super Mario 64 so fantastic. As each fight progresses in difficulty, your confidence in actually being able to defeat this overgrown turtle starts to diminish. By the time you reach the final stand-off, Bowser has made quite an impression on you that will carry through the entire fight until his glorious defeat. The sense of player accomplishment is incredible.