Fallout 76: 10 Take-Aways From Bethesda's E3 Conference
7. Gameplay
Lots of the gameplay shown seems very similar to Fallout 4.
The HUD, animations and combat specifics, even down to sound effects and the stealth system, seem identical to that of Fallout 4, albeit with some minor aesthetic tweaks.
One interesting difference from previous games was the prevalence of harder monsters - many times big monsters were shot in gameplay trailers hardly any damage was done, as opposed to other Fallouts in which only survival mode posed any challenge.
All the gameplay trailers only showed combat, however, so it's possible that there will be major changes to gameplay mechanics such as hacking and healing, or other Pip-Boy related functions.
The gameplay and menu style of settlement mode also seems a lot more intelligent now, and is styled like a city-building game more than Fallout 4.