15 Best TV Villains In The Marvel Cinematic Universe
9. Agent 33
Appeared In: Agents of S.H.I.E.L.D.
Ex-SHIELD agent Kara Palamas was brainwashed early in the second season by Daniel Whitehall and turned into a weapon of HYDRA, complete with the nano mask that allowed her to assume the identity of others, which backfired when Melinda May's face was scarred onto her own.
After Whitehall's death, Agent 33 allied herself with Ward, who "freed" her, giving her back her sense of self and helping to restore her own face. Later taken back into SHIELD custody, 33 escaped by once again using May's identity and kidnapped Bobbi, luring the agents into a trap as revenge for all she had gone through.
Because Melinda May is awesome, she tricked Ward into killing 33, bringing an end to the conflicted antagonist while inevitably catapulting Ward even further down his own path of villainy.