Family Guy: 10 Best Characters Who Only Appeared In One Episode

Glenn Quagmire often found himself getting into trouble with the ladies, but in most cases, he didn't keep any of them around for long. Whenever the 61-year-old pilot did end up committed, though, it usually placed him at the center of a desperate (and often awkward) situation. Such was the case during "The Giggity Wife."

Peter Griffin and the boys discovered Joe Swanson kept a Harvard ID card from one of the kids he encountered, so the group ended up going to the campus and having a wild night. Along the way, Quagmire managed to marry a woman named Charmisse, who turned out to be (how to put this kindly) a prostitute.

Quagmire attempted to get out of the marriage, but his new wife refused to leave. He then tried to make her a classier lady instead, which didn't turn out to be fruitful. Finally, he settled on pretending to be gay with Peter, but Charmisse stopped the act, noting she would support the divorce.

While she thanked Quagmire for being "decent" with her, Charmisse was still treated pretty poorly by the Quahog pervert. That wasn't to say she didn't get some revenge before disappearing from the series altogether, though. After Charmisse stopped Quagmire and Peter from copulating to get out of the marriage, the two friends celebrated only to realize a computer camera recorded them all along. On the other side, was a traumatized Griffin family.