Star Trek: Endgame Fiction Vs. Reality

What Happens In The Episode:

Although not directly seen in the episode, the shadow of The Borg still looms over The Federation in 2404. The mere concept of The Borg carried enough weight that specifically anti-Borg technology is utilised in Starfleet, and an entire semester would be dedicated to them at The Academy under Reginald Barclay's tutelage. In this alternate timeline, Admiral Janeway 'literally wrote the book on The Borg', and joins Barclay as a guest lecturer for the cadets.

What Really Happened:

Janeway's journey into the past was originally only intended to get Voyager home through a Borg trans-warp conduit, but the younger Captain uses the opportunity to infect The Borg with a neurolytic pathogen, crippling them by tricking The Queen into assimilating the older Janeway.

Following this devastating blow, The Borg's status as a galactic threat diminishes. Derelict cubes litter the quadrant to be studied by various species, alongside the liberated drones (Ex-Bs), although a great deal of suspicion and prejudice still surrounded this new sub-species.

Following some more time travelling tomfoolery at the hands of Q, a new Borg Queen finally emerges in Picard Season 2, fused with Dr. Agnes Jurati and allying this new co-operative collective with The Federation as mysterious a new threat looms.

That's not all - Picard's third season reveals that another Queen, this time played vocally once again by Alice Krige, has parked her Cube in the clouds of Jupiter. This is the closest the Borg ever come to actually assimilating the Federation, though thankfully the bridge crew of the Enterprise-D are on hand to save the day. It looks like this may, in fact, be the end of the Borg.